Key result
A systemic immune-inflammation index cut-off of 563 predicted atrial fibrillation recurrence after successful direct current cardioversion with 96.9% sensitivity and 55.2% specificity (p<0.001).
Why the study?
It was unknown whether a relationship exists between the systemic immune-inflammation index and atrial fibrillation recurrence following successful direct current cardioversion.
Does the systemic immune-inflammation (SII) index predict the recurrence of atrial fibrillation in patients with persistent atrial fibrillation after successful direct current cardioversion?
Cohort (n=99)
Does the systemic immune-inflammation (SII) index predict the recurrence of atrial fibrillation in patients with persistent atrial fibrillation after successful direct current cardioversion?
The systemic immune-inflammation index is a simple, highly sensitive biomarker that can independently predict atrial fibrillation recurrence following successful direct current cardioversion.
Background: We aimed to determine whether there is a relationship between the systemic immune-inflammation (SII) index and the recurrence of atrial fibrillation (AF) after successful direct current cardioversion (DCCV). Methods: The study included 99 patients with persistent AF who underwent successful cardioversion between 2015 and 2020. Results: In multiple regression analyses, the SII index was found to be a better independent predictor of AF recurrence after successful DCCV (p < 0.001). The cut-off value of SII (563) was associated with 96.9% sensitivity and 55.2% specificity to predict AF recurrence after DCCV. Conclusion: As a simple biomarker, SII index is an independent parameter for predicting AF recurrence after successful DCCV in patients with persistent AF. Also, SII levels can predict AF recurrence better than neutrophil-to-lymphocyte ratio.
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Kuş et al. (2022) conducted a cohort in Persistent atrial fibrillation (n=99). Systemic immune-inflammation (SII) index vs. Neutrophil-to-lymphocyte ratio was evaluated on Atrial fibrillation recurrence (p=<0.001). A systemic immune-inflammation index cut-off of 563 predicted atrial fibrillation recurrence after successful direct current cardioversion with 96.9% sensitivity and 55.2% specificity (p<0.001).
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