Key points are not available for this paper at this time.
This review of the mechanism of pulmonary hypertension is focused on pulmonary arterial hypertension, a disorder that can be idiopathic or can occur in association with other disorders, such as infection with the human immunodeficiency virus. The authors suggest that an abnormality involving intracellular signaling mediated by transforming growth factor β underlies the various forms of pulmonary arterial hypertension.
Farber et al. (Wed,) studied this question.