Population
Mouse retinal vessels and endothelial cells (in vitro and in vivo)
Design
Preclinical
Authors
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YAP-ANG-2 signaling may regulate angiogenesis in preclinical models; hypothesis-generating and should not yet inform clinical practice.
YAP acts as a critical regulator in angiogenesis by mediating VE-cadherin-dependent cell contacts and regulating ANG-2 expression.
Choi et al. (2015) studied this question.
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