Cardiac T1 Mapping and Extracellular Volume (ECV) in clinical practice: a comprehensive review
Why the study?
Does cardiac T1 mapping and ECV assessment improve the detection of diffuse myocardial fibrosis compared to LGE in patients with cardiomyopathies?
Population
Patients with ischaemic and non-ischaemic cardiomyopathies and acute chest pain syndromes
Comparison
Cardiac T1 mapping and Extracellular Volume… vs Late Gadolinium Enhancement (LGE)
Design
Review
Authors
Discussion
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Member takes
Implication
May aid tissue characterization where LGE is limited; leaves open prospective validation before routine adoption.
Structured PICO
Does cardiac T1 mapping and ECV assessment improve the detection of diffuse myocardial fibrosis compared to LGE in patients with cardiomyopathies?
P
Population
Patients with ischaemic and non-ischaemic cardiomyopathies and acute chest pain syndromes
I
Intervention
Cardiac T1 mapping and Extracellular Volume (ECV) assessment
C
Comparator
Late Gadolinium Enhancement (LGE)
O
Outcome
Detection and quantification of focal and diffuse alterations in myocardial structuresurrogate
Cardiac T1 mapping and ECV assessment provide valuable non-invasive tissue characterization for detecting diffuse myocardial fibrosis that may be missed by standard LGE imaging.
Cite This Study
Haaf et al. (2016) studied this question.