Standardized phantom study validates MRI-PDFF for liver fat quantification, suggesting need for harmonization across centers.
MRI-PDFF is an accurate, precise, and consistent biomarker for liver fat quantification across different vendors and field strengths. The minor, systematic inter-vendor biases observed are likely due to proprietary algorithmic differences and, while quantitatively small, highlight the need for harmonization in multi-center clinical trials.
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Yen et al. (2026) studied this question.
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