Dexmedetomidine with local anesthetics was associated with a delay in consumption of the first analgesic in the postoperative period, decrease in the amount of rescue intravenous tramadol and in the VAS scores at 6, 12 and 24 hours. However, the GRADE assessment of the quality of evidence was 'low' due to the high risk of bias and heterogeneity.
Novaes et al. (Mon,) studied this question.