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The aim is to evaluate methodologies for extracting and analyzing phenolic compounds and their antioxidant activity.

April 8, 2026Methods and ProtocolsOpen Access

Phenolic Compounds and Antioxidant Activity: Analytical Methods and Current Knowledge—A Review

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The aim is to evaluate methodologies for extracting and analyzing phenolic compounds and their antioxidant activity.
Critical review of extraction and detection methodologies
Comparison of conventional and advanced extraction techniques
Evaluation of in vitro, in vivo, and ex vivo approaches
Discussion of spectrophotometric, electrochemical, and chromatographic detection methods
Lack of standardization in methodologies limits accurate assessment of antioxidant activity
Variations in extraction techniques impact analysis reliability
Combining traditional methods with innovative techniques can enhance extraction efficiency

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This review evaluates methods for assessing antioxidant activity of phenolic compounds, indicating critical research gaps.

Lisjak et al. (2026) studied this question.

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