Objective: Post-void residual urine (PVR) is commonly evaluated during the assessment and follow-up of patients with benign prostate hyperplasia (BPH). We investigated in our study whether voiding of the patients when they had a sense of urinary urgency in the environment of uroflowmetry may cause a high and inaccurate volume of PVR. Material and Methods: 101 patients over 50 years applied to our outpatient clinic due to bladder outlet obstruction related to BPH were included in the study. Patients were instructed to void in restroom upon experiencing a normal desire to urinate. Subsequently, PVR1 and prostate volumes were measured using transabdominal ultrasonography. Later on the same day, after fluid intake and the onset of a severe bladder fullness sensation, uroflowmetry was performed. PVR2 was then measured by the same physician on the same day. Demographic data, laboratory parameters, and ultrasonographic measurements of the patients were compared. Results: We found in this study that the difference in PVR2-PVR1 volume was significantly high 55 mL (-125, 250) (p<0.001) and was similar in the patients taking alpha-blockers. This difference was positively correlated with prostate volume and prostate-specific antigen values (r=0.341, p<0.001; r=0.319, p=0.001, respectively) whereas negatively correlated with the maximum and average flow rates in uroflowmetry (r=-0.216, p=0.03; r=-0.212, p=0.033, respectively). Conclusion: Falsely elevated PVR measurements may result in diagnostic misclassification, overtreatment, or unnecessary interventions. Assessing PVR after a normal desire to void and standardizing measurement conditions could improve diagnostic accuracy and patient management in BPH-related bladder outlet obstruction.
HEPŞEN et al. (Thu,) studied this question.
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