Key result
Logistic regression and linear discriminant models outperform other ML algorithms in predicting heart disease risk.
Why the study?
Traditional diagnostic approaches for heart disease rely on clinical examinations and expensive medical tests that may not be accessible in all healthcare environments.
Do machine learning algorithms accurately predict the presence of heart disease using basic clinical parameters?
Do machine learning algorithms accurately predict the presence of heart disease using basic clinical parameters?
Machine learning models, particularly Logistic Regression and Linear Discriminant Analysis, can effectively predict heart disease risk using standard clinical parameters.
Supports ML exploration for heart disease prediction in clinic; leaves open real-world utility pending prospective validation.
Heart disease remains one of the leading causes of death worldwide, making early detection and accurate diagnosis essential for improving patient outcomes. Traditional diagnostic approaches often rely on clinical examinations and expensive medical tests, which may not always be accessible in all healthcare environments. In this research, we explore the use of machine learning techniques to develop an intelligent system for predicting the presence of heart disease using clinical parameters such as age, gender, blood pressure, cholesterol level, and heart rate. The dataset used in this study contains labelled medical records that are pre-processed, balanced, and divided into training and testing sets to ensure reliable model evaluation. Several supervised machine learning algorithms, including Logistic Regression, Support Vector Machines, Naïve Bayes, Decision Trees, K-Nearest Neighbors, and Linear Discriminant Analysis, are implemented and compared to identify the most effective model for heart disease diagnosis. Feature selection techniques are applied to determine the most influential clinical attributes contributing to disease prediction. To evaluate model performance, we employ a 5-fold cross-validation approach along with evaluation metrics such as accuracy, precision, recall, F1-score, and area under the ROC curve (AUC).Experimental results demonstrate that the Logistic Regression and Linear Discriminant models achieve the highest prediction accuracy, showing strong capability in identifying heart disease risk from clinical data. In addition, the integration of optimized feature selection methods improves the overall diagnostic performance while reducing computational complexity. The proposed machine learning framework provides an effective and scalable approach for supporting early heart disease detection and assisting healthcare professionals in clinical decision-making.
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Dr.K.ChandraSekhar et al. (2026) studied this question. Logistic Regression and Linear Discriminant models achieved the highest accuracy in predicting heart disease risk from clinical parameters, outperforming other machine learning algorithms.
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