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April 8, 2026JAMA Pediatrics2 citations

Youth Suicide and the Evidence Paradox

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NNNilson N. Mendes NetoJMJessika M Mendes

Key Points

  • This viewpoint aims to analyze the paradox in evidence gathering regarding youth suicide, focusing on at-risk populations.
  • Discussion of youth suicide rates in the US
  • Examination of challenges in conducting randomized clinical trials
  • Analysis of evidence paradox in prevention efforts
  • Identifies populations at greatest risk for youth suicide
  • Discusses difficulties in conducting clinical trials in these populations
  • Highlights gaps in prevention strategies due to lack of evidence from trials

Abstract

This Viewpoint discusses youth suicide rates in the US and how an evidence paradox—the populations at greatest risk are those in which randomized clinical trials are the most difficult to conduct—has affected prevention efforts.

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Cite This Study

Neto et al. (2026) studied this question.

synapsesocial.com/papers/69d5f09e74eaea4b11a7a164https://doi.org/10.1001/jamapediatrics.2026.0275
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