Intravesical Platelet-Rich Plasma Injection for Refractory Interstitial Cystitis/Painful Bladder Syndrome: A Systematic Review and Meta-analysis

Intravesical PRP injection may represent a promising therapeutic option for refractory IC/BPS, showing trends toward improvement in pain, nocturia, frequency, and bladder capacity. However, as current evidence is derived exclusively from uncontrolled and non-randomized studies, its efficacy remains uncertain and the findings should be interpreted with caution. Nonetheless, higher-quality randomized controlled trials are required to confirm its efficacy and better define its role in clinical practice.