Key result
Frailty linked to higher 1-year mortality and MACCE following mitral TEER.
Why the study?
Does frailty increase the risk of 1-year mortality and MACCE in patients undergoing Mitral Transcatheter Edge-to-Edge Repair?
Does frailty increase the risk of 1-year mortality and MACCE in patients undergoing Mitral Transcatheter Edge-to-Edge Repair?
Incorporating frailty assessment into pre-procedural evaluation for MTEER is important for risk stratification, as frailty significantly increases 1-year mortality, MACCE, and readmissions.
Supports pre-MTEER frailty assessment for risk stratification; reinforces prognostic value across prior observational cohorts.
Summary Frailty is independently associated with significantly higher 1‐year mortality and MACCE following MTEER. Frail patients also demonstrated increased risks of HF exacerbation, major bleeding, and readmission. Incorporating frailty assessment into pre‐procedural evaluation may improve risk stratification and guide personalized management strategies.
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Jain et al. (2026) studied this question. Frailty is independently associated with significantly higher 1-year mortality and MACCE following mitral transcatheter edge-to-edge repair.
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