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April 8, 2026European Journal Of Haematology

Loncastuximab Tesirine in Relapsed/Refractory Diffuse Large B‐Cell Lymphoma: Evidence and Practical Guidance From Italian Clinical Experience

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Authors

FBFrancesca BonelloAAAndrea AroldiACAlessia Castellino

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Overview

Clinical evidence demonstrates the efficacy of loncastuximab tesirine in relapsed/refractory diffuse large B-cell lymphoma, suggesting its importance in treatment options.

Key Points

  • To evaluate the clinical evidence and practical guidance for using loncastuximab tesirine in R/R DLBCL.
  • Overview of clinical evidence for loncastuximab tesirine
  • Description of three clinical cases
  • Discussed management and safety during treatment
  • Explored use as a bridge to allogeneic stem cell transplantation
  • Efficacy of loncastuximab tesirine illustrated in clinical cases
  • Demonstrated safety profile
  • Highlighted its role in therapy sequencing for R/R DLBCL

Cite This Study

Bonello et al. (2026) studied this question.

synapsesocial.com/papers/69d5f10974eaea4b11a7a85bhttps://doi.org/10.1111/ejh.70183
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