Placental DNA methylation mediates the prenatal maternal stress‐childhood allergy association: A cohort study

Key Points

• This study aims to explore how prenatal maternal stress influences childhood allergies through changes in placental DNA methylation.
• Cohort study design
• Assessment of maternal stress levels during pregnancy
• Analysis of placental DNA methylation patterns
• Evaluation of childhood allergy outcomes
• Prenatal maternal stress correlates with altered placental DNA methylation
• Children exposed to high maternal stress show higher rates of allergies
• Methylation changes serve as potential biomarkers for allergies in childhood