Sensing in reverse: Reversible detection of as few as 109 molecules (1700 aM) of dimethyl methylphosphonate, a nerve agent simulant, is demonstrated at the end of a micro GC column (see picture). Such arrays form the basis of rapidly transducing molecular sensors with micrometer-sized footprints. The separation capability of the column eliminates the need for selectivity on the sensor, as long as analyte binding is reversible and rapid. Detailed facts of importance to specialist readers are published as "Supporting Information". Such documents are peer-reviewed, but not copy-edited or typeset. They are made available as submitted by the authors. Please note: The publisher is not responsible for the content or functionality of any supporting information supplied by the authors. Any queries (other than missing content) should be directed to the corresponding author for the article.
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Lee et al. (2008) studied this question.
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