Comparative study reveals circulating tumor cells in metastatic carcinomas but not nonmalignant controls, indicating their diagnostic utility.
The CellSearch system can be standardized across multiple laboratories and may be used to determine the clinical utility of CTCs. CTCs are extremely rare in healthy subjects and patients with nonmalignant diseases but present in various metastatic carcinomas with a wide range of frequencies.
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Allard et al. (2004) studied this question.
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