Retrospective cohort study reveals increased 30-day mortality from preinjury warfarin but not antiplatelets in head trauma patients, suggesting a need for heightened monitoring.
The use of warfarin before trauma was associated with increased 30-day mortality among a subset of patients. Use of platelet inhibitors before trauma was not associated with increased mortality. These results indicate that patients on preinjury warfarin may need closer monitoring and follow up after trauma despite normal physiology on admission to the emergency department.
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Narum et al. (2016) studied this question.
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