What question did this study set out to answer?

To determine the impact of preinjury warfarin use on the risk of fatal hemorrhagic complications in trauma patients.

Complications of Preinjury Warfarin Use in the Trauma Patient

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Prospective evaluation of trauma patients on warfarin shows no increased mortality risk compared to non-users.

To determine the impact of preinjury warfarin use on the risk of fatal hemorrhagic complications in trauma patients.
Evaluated 159 trauma patients on warfarin and age-matched patients not on warfarin.
Compared outcomes focusing on head trauma and intracranial injuries.
Conducted statistical analyses on mortality and injury outcomes.
9.4% of patients on warfarin died (15 deaths), with no significant difference in INR values between survivors and non-survivors (p=0.585).
48% of deaths (12) occurred in patients with intracranial injuries, compared to 10% (5) in non-warfarin patients (p<0.001).
Loss of consciousness was identified in 10 of 12 warfarin patients who died with intracranial injuries.

Mina et al. (2003) studied this question.

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