Does being overweight or obese reduce mortality compared to normal or underweight in patients with acute coronary syndromes?
This registry study supports the obesity paradox in ACS, showing lower mortality in overweight and obese patients compared to normal and underweight patients.
In this large and unselected group of patients with ACSs, the relation between BMI and mortality was U-shaped, with the nadir among overweight or obese patients and underweight and normal-weight patients having the highest risk. These data strengthen the concept of the obesity paradox substantially.
Angerås et al. (Tue,) studied this question.