Why the study?
Is progressive fluid overload an earlier and more sensitive predictor of mortality and longer intensive care stay compared to changes in serum creatinine in post cardiac surgery patients?
Is progressive fluid overload an earlier and more sensitive predictor of mortality and longer intensive care stay compared to changes in serum creatinine in post cardiac surgery patients?
Monitoring progressive fluid overload may allow for earlier intervention and more effective control of renal and cardiac dysfunction after cardiac surgery compared to relying solely on serum creatinine changes.
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Hypothesis-generating for fluid overload monitoring after cardiac surgery; leaves open prospective validation versus creatinine for mortality and ICU stay.
Although both fluid overload and changes in serum creatinine are prognostic markers after cardiac surgery, it seems that progressive fluid overload may be an earlier and more sensitive marker of renal dysfunction affecting heart function and, as such, it would allow earlier intervention and more effective control in post cardiac surgery patients.
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Stein et al. (2012) studied this question.
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