Does the Relation of Blood Pressure to Coronary Heart Disease Risk Change With Aging?

Stanley S. Franklin; Martin G. Larson; Shehzad Akbar Khan; Nathan D. Wong; Eric Leip; William B. Kannel; Daniel Levy

doi:10.1161/01.cir.103.9.1245

March 6, 2001CirculationOpen Access

Does the Relation of Blood Pressure to Coronary Heart Disease Risk Change With Aging?

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Why the study?

Does the relation of blood pressure indices (DBP, SBP, PP) to coronary heart disease risk change with aging?

Key Points

To determine whether the predictive power of different blood pressure indexes for coronary heart disease risk changes across age groups.
Evaluated the association of diastolic blood pressure, systolic blood pressure, and pulse pressure with coronary heart disease risk across age strata (<50, 50–59, and ≥60 years).
Diastolic blood pressure was the strongest predictor of coronary heart disease risk in individuals younger than 50 years of age.
Patients aged 50 to 59 years experienced a transition phase in which diastolic blood pressure, systolic blood pressure, and pulse pressure were comparable predictors.
In individuals 60 years of age and older, diastolic blood pressure was negatively associated with coronary heart disease risk, rendering pulse pressure superior to systolic blood pressure.

Structured PICO

Does the relation of blood pressure indices (DBP, SBP, PP) to coronary heart disease risk change with aging?

P

Population

Patients evaluated for coronary heart disease (CHD) risk across different age groups (<50 years, 50 to 59 years, and ≥60 years)

I

Intervention

Blood pressure indices (diastolic blood pressure [DBP], systolic blood pressure [SBP], and pulse pressure [PP])

O

Outcome

Coronary heart disease (CHD) riskhard clinical

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Implication

The predictive value of different blood pressure components for coronary heart disease risk changes significantly with age, shifting from diastolic blood pressure in younger patients to pulse pressure in older patients.

Abstract

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Cite This Study

Franklin et al. (2001) studied this question.

synapsesocial.com/papers/69d6b4c941375cf86eed8878 https://doi.org/10.1161/01.cir.103.9.1245

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Does the Relation of Blood Pressure to Coronary Heart Disease Risk Change With Aging?

Key Points

Structured PICO

Ask about this paper

Implication

Abstract

Discussion

Cite This Study

Does the Relation of Blood Pressure to Coronary Heart Disease Risk Change With Aging?

Key Points

Structured PICO

Ask about this paper

Implication

Abstract

Discussion

Cite This Study

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