The effects of a long-duration intravenous infusion of detomidine, with and without vatinoxan, on equine energy metabolism and urine composition

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Vatinoxan alleviated detomidine-induced hypoinsulinaemia and hyperglycaemia and diminished urination frequency, glucosuria, and natriuresis during and after a 4 hour CRI. Vatinoxan may be beneficial during standing sedation with alpha2-adrenoceptor agonists.