Associations of Depression, Anxiety, Worry, Perceived Stress, and Loneliness Prior to Infection With Risk of Post–COVID-19 Conditions

Siwen Wang; Luwei Quan; Jorge E. Chavarro; Natalie Slopen; Laura D. Kubzansky; Karestan C. Koenen; Jae H. Kang; Marc G. Weisskopf; Westyn Branch‐Elliman; Andrea L. Roberts

doi:10.1001/jamapsychiatry.2022.2640

September 7, 2022JAMA PsychiatryOpen Access

Associations of Depression, Anxiety, Worry, Perceived Stress, and Loneliness Prior to Infection With Risk of Post–COVID-19 Conditions

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Key Points

To investigate whether psychological distress experienced prior to SARS-CoV-2 infection increases the risk of developing post-COVID-19 conditions.
Assessed preinfection psychological distress factors, including depression, anxiety, worry, perceived stress, and loneliness.
Followed individuals after SARS-CoV-2 infection to track the onset and persistence of post-COVID-19 symptoms.
Preinfection psychological distress is significantly associated with an elevated risk of developing post-COVID-19 conditions.
The findings highlight a need to investigate underlying biobehavioral mechanisms that link psychological vulnerability to prolonged postinfection recovery.

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Implication

Observational study reveals preinfection psychological distress elevates post-COVID-19 conditions in infected individuals, indicating a potential biobehavioral link to persistent symptoms.

Abstract

The findings of this study suggest that preinfection psychological distress may be a risk factor for post-COVID-19 conditions in individuals with SARS-CoV-2 infection. Future work should examine the biobehavioral mechanism linking psychological distress with persistent postinfection symptoms.

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Wang et al. (2022) studied this question.

synapsesocial.com/papers/69d6b5b875cae9790bed88f9 https://doi.org/10.1001/jamapsychiatry.2022.2640

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Associations of Depression, Anxiety, Worry, Perceived Stress, and Loneliness Prior to Infection With Risk of Post–COVID-19 Conditions

Key Points

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Implication

Abstract

Discussion

Cite This Study

Associations of Depression, Anxiety, Worry, Perceived Stress, and Loneliness Prior to Infection With Risk of Post–COVID-19 Conditions

Key Points

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Implication

Abstract

Discussion

Cite This Study

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