What question did this study set out to answer?

To develop and evaluate a multiplexed echo planar imaging sequence that significantly accelerates whole-brain functional and diffusion MRI acquisition without compromising spatial resolution.

December 20, 2010PLoS ONEOpen Access

Multiplexed Echo Planar Imaging for Sub-Second Whole Brain FMRI and Fast Diffusion Imaging

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Authors

DFDavid A. FeinbergNeurosciences Institute SMSteen MoellerUniversity of Minnesota SSStephen M. SmithJohn Radcliffe Hospital

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Implication

Imaging study demonstrates sub-second whole-brain functional MRI using multiplexed echo planar imaging, suggesting enhanced sensitivity for dynamic neural network analysis.

Key Points

To develop and evaluate a multiplexed echo planar imaging sequence that significantly accelerates whole-brain functional and diffusion MRI acquisition without compromising spatial resolution.
Integrated temporal multiplexing using simultaneous echo refocused (SIR) EPI with spatial multiplexing using multibanded (MB) radiofrequency pulses to generate m×n images per echo train.
Tested the pulse sequence at 3 Tesla and 7 Tesla field strengths during resting-state fMRI and high angular resolution diffusion imaging (HARDI).
Reduced whole-brain fMRI repetition times to 400 ms and 800 ms at 3 Tesla (compared to conventional 2.5 s) and shortened HARDI scan times by 2- to 4-fold.
Lowered the specific absorption rate at 7 Tesla via simultaneous spin-echo refocusing and eliminated the need for fat suppression pulses by shifting fat signal out of plane.
Increased peak functional sensitivity by 60% during resting-state network detection via independent component analysis due to a 6-fold higher sampling rate.

Cite This Study

Feinberg et al. (2010) studied this question.

synapsesocial.com/papers/69d6bb2df174babf6cab3502 https://doi.org/10.1371/journal.pone.0015710

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Implication

Imaging study demonstrates sub-second whole-brain functional MRI using multiplexed echo planar imaging, suggesting enhanced sensitivity for dynamic neural network analysis.

Multiplexed Echo Planar Imaging for Sub-Second Whole Brain FMRI and Fast Diffusion Imaging

Discussion

Member takes

Implication

Key Points

Cite This Study

Multiplexed Echo Planar Imaging for Sub-Second Whole Brain FMRI and Fast Diffusion Imaging

Discussion

Member takes

Implication

Key Points

Cite This Study

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