Why the study?
Does early pharmacologic VTE prophylaxis reduce thromboembolic complications in patients who underwent urgent neurosurgical interventions for traumatic brain injury?
Population
Patients who underwent urgent neurosurgical interventions for TBI
Comparison
Early pharmacologic VTE prophylaxis vs later initiation
Design
Cohort study
Authors
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Caution advised against initiation within 3 days after TBI neurosurgery; leaves optimal VTE prophylaxis timing open for RCTs.
Does early pharmacologic VTE prophylaxis reduce thromboembolic complications in patients who underwent urgent neurosurgical interventions for traumatic brain injury?
Early VTE prophylaxis after urgent TBI neurosurgery reduces thromboembolism but increases the risk of repeated neurosurgery if initiated within the first 3 days.
Byrne et al. (2021) studied this question.
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