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December 1, 1997The Journal of Experimental MedicineOpen Access

In Vivo Microbial Stimulation Induces Rapid CD40 Ligand–independent Production of Interleukin 12 by Dendritic Cells and their Redistribution to T Cell Areas

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Authors

CSCaetano Reis e SousaScripps Research InstituteSHSara HienyNational Institutes of HealthTSTanya Scharton‐KerstenInternational AIDS Vaccine Initiative

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Sousa et al. (1997) studied this question.

synapsesocial.com/papers/69d6bcd141375cf86eed898chttps://doi.org/10.1084/jem.186.11.1819
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Also Consider

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  2. 2Dendritic cells produce IL-12 and direct the development of Th1 cells from naive CD4+ T cells.1995 · 1,548 citations
  3. 3Regulation of murine macrophage IL-12 production. Activation of macrophages in vivo, restimulation in vitro, and modulation by other cytokines1996 · 232 citations
  4. 4Humoral immune responses in CD40 ligand-deficient mice.1994 · 541 citations
  5. 5Interleukin‐12 is produced by dendritic cells and mediates T helper 1 development as well as interferon‐γ production by T helper 1 cells1996 · 709 citations