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Case report demonstrates persistent phrenic nerve injury following pulsed field ablation, highlighting the importance of anatomical reconstruction and electrode positioning.
Pulsed field ablation (PFA) is increasingly being adopted as an effective and safe method for pulmonary vein (PV) isolation. Compared to conventional thermal ablation methods such as radiofrequency and cryoablation, PFA selectively targets myocardial tissue while sparing surrounding structures. With previous studies having demonstrated its efficacy and safety,1,2 PFA is considered less likely to cause damage to non-cardiac tissues, including nerves and the esophagus.
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Oda et al. (2025) studied this question.
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