Why the study?
Does NF-kappaB inhibition attenuate cardiac hypertrophy and alter stress-induced LV remodelling?
Does NF-kappaB inhibition attenuate cardiac hypertrophy and alter stress-induced LV remodelling?
NF-kappaB appears to be required for adaptive cardiac hypertrophy, as its inhibition attenuates hypertrophy in a gender-specific manner without altering the course of stress-induced LV remodelling.
NF-kappaB inhibition attenuates cardiac hypertrophy in a gender-specific manner but does not alter the course of stress-induced LV remodelling, indicating NF-kappaB to be required for adaptive cardiac hypertrophy.
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Zelarayán et al. (2009) studied this question.
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