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Demonstrates improved antibiotic release from bone cement by predissolving vancomycin or amphotericin B in water, highlighting an efficient preparation method.
Adding vancomycin or amphotericin B antibiotic powder in distilled water before mixing with bone cement can significantly improve the efficiency of antibiotic release than can loading ALBC with the same dose of antibiotic powder. This simple and effective method for preparation of ALBCs can significantly improve the efficiency of antibiotic release in ALBCs. Cite this article: Bone Joint Res 2014;3:246-51.
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Chang et al. (2014) studied this question.
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