April 21, 2023Journal of Anesthesia45 citationsOpen Access

Post-induction hypotension and intraoperative hypotension as potential separate risk factors for the adverse outcome: a cohort study

SCSzymon CzajkaMedical University of Silesia ZPZbigniew PutowskiJagiellonian University ŁKŁukasz J. KrzychMedical University of Silesia

Structured PICO

Does intraoperative hypotension or post-induction hypotension increase the risk of post-operative organ complications in surgical patients?

Population

Surgical patients (specific demographics, inclusion/exclusion criteria, and sample size not reported in abstract)

Intervention

Intraoperative hypotension (IOH) defined as MAP ≤ 65 mmHg, and post-induction hypotension (PIH)

Outcome

Post-operative organ complications and adverse outcomes

Intraoperative hypotension (MAP ≤ 65 mmHg) is associated with post-operative organ complications, though comparisons with post-induction hypotension are complicated by differences in cumulative duration.

Abstract

The presence of IOH defined as MAP ≤ 65 mmHg is relevant to post-operative organ complications, the presence of PIH does not appear to be of such significance. Because cumulative duration of PIH and IOH differs significantly, especially in long-lasting procedures, direct comparison of the influence of PIH and IOH on outcome separately may be biased and should be taken into account in data interpretation. Further research is needed to deeply investigate this phenomenon.

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