Why the study?
What are the predictors of clinically significant hypotension after the induction of general anesthesia?
Population
4,096 patients undergoing general anesthesia
Comparison
Induction of general anesthesia vs Patients without specific risk factors or…
Design
Cohort
Follow-up
0-10 minutes postinduction; postoperative period
Authors
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Identified predictors may warrant vigilance at induction in at-risk patients; leaves open whether targeted interventions reduce hypotension.
What are the predictors of clinically significant hypotension after the induction of general anesthesia?
Propofol induction, increasing fentanyl dose, age >=50 years, ASA class III-V, and baseline MAP <70 mmHg are significant predictors of severe postinduction hypotension, which is associated with worse postoperative outcomes.
Reich et al. (2005) studied this question.
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