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April 25, 2006Circulation722 citations

Role of T Lymphocytes and Interferon-γ in Ischemic Stroke

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GYGökhan YılmazState HospitalTAThiruma V. ArumugamLa Trobe UniversityKSKaren Y. StokesLouisiana State University Health Sciences Center Shreveport

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Abstract

These findings indicate that CD4+ and CD8+ T lymphocytes, but not B lymphocytes, contribute to the inflammatory and thrombogenic responses, brain injury, and neurological deficit associated with experimental stroke. Although IFN-gamma plays a pivotal role in stroke-induced inflammatory responses, T lymphocytes appear to be a minor source of this cytokine.

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Yılmaz et al. (2006) studied this question.

synapsesocial.com/papers/69d6f30675cae9790bed8e83https://doi.org/10.1161/circulationaha.105.593046
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