What question did this study set out to answer?

To introduce FastME 2.0, an updated distance-based phylogeny inference program designed to improve tree topology searches and computational efficiency.

June 30, 2015Molecular Biology and EvolutionOpen Access

FastME 2.0: A Comprehensive, Accurate, and Fast Distance-Based Phylogeny Inference Program: Table 1.

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Authors

VLVincent LefortCentre National de la Recherche Scientifique RDRichard DesperRutgers, The State University of New Jersey OGOlivier GascuelUniversité de Technologie de Compiègne

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Implication

Software evaluation demonstrates accurate distance-based phylogeny inference in molecular sequences, highlighting scalable evolutionary tree reconstruction.

Key Points

To introduce FastME 2.0, an updated distance-based phylogeny inference program designed to improve tree topology searches and computational efficiency.
Implemented balanced minimum evolution principles with topological search algorithms, extending previous Nearest Neighbor Interchange to include Subtree Pruning and Regrafting.
Incorporated distance estimation models for DNA and protein sequences, bootstrap resampling, and parallel computing capabilities across command-line, PHYLIP-like, and web interfaces.
FastME 2.0 matches Neighbor Joining computational speeds while achieving refined tree topologies via Subtree Pruning and Regrafting.
Enables parallel processing and versatile sequence distance modeling across automated analysis pipelines and user-accessible web servers.

Cite This Study

Lefort et al. (2015) studied this question.

synapsesocial.com/papers/69d6fa2c5413bc3de5ab3207 https://doi.org/10.1093/molbev/msv150

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Implication

Software evaluation demonstrates accurate distance-based phylogeny inference in molecular sequences, highlighting scalable evolutionary tree reconstruction.

FastME 2.0: A Comprehensive, Accurate, and Fast Distance-Based Phylogeny Inference Program: Table 1.

Discussion

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Implication

Key Points

Cite This Study

FastME 2.0: A Comprehensive, Accurate, and Fast Distance-Based Phylogeny Inference Program: Table 1.

Discussion

Member takes

Implication

Key Points

Cite This Study

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