Why the study?
Does maternal obesity increase the risk and severity of NAFLD in offspring?
Does maternal obesity increase the risk and severity of NAFLD in offspring?
Maternal obesity is associated with an increased risk and severity of NAFLD in offspring.
Maternal obesity may heighten offspring NAFLD risk; hypothesis-generating and should not yet change practice.
In a study of all young persons in Sweden with a liver biopsy consistent with fatty liver, the authors found that compared to matched controls, the risk of fatty liver was much higher in those with obese mothers. This was independent of available confounders and suggests that the high prevalence of obesity in younger persons might lead to a higher risk of fatty liver in their offspring.
No takes yet. Share an insight, caveat, or question.
Hagström et al. (2021) studied this question.
Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context: