Renal cell carcinoma with inferior vena cava involvement: Prognostic effect of tumor thrombus consistency on cancer specific survival

René Mager; Siamak Daneshmand; Christopher P. Evans; Joan Palou; Juan Ignacio Martínez‐Salamanca; Viraj A. Master; James M. McKiernan; John A. Libertino; Axel Haferkamp; Axel Haferkamp; Umberto Capitanio; Joaquı́n Carballido; V. Chantada; Thomas Chromecki; Gaetano Ciancio; Siamak Daneshmand; Christopher P. Evans; Paolo Gontero; Javier García González; Markus Hohenfellner; William C. Huang; Theresa M. Koppie; John A. Libertino; Estefanía Linares; Adam Lorentz; Juan Ignacio Martínez‐Salamanca; Viraj A. Master; James M. McKiernan; Francesco Montorsi; Giacomo Novara; Padraic O’Malley; Sascha Pahernik; Joan Palou; J.L. Pontones Moreno; Raj S. Pruthi; Ó. Rodríguez Faba; Paul Russo; Douglas S. Scherr; Shahrokh F. Shariat; Martin Spahn; Carlo Terrone; Derya Tilki; Dario Vázquez‐Martul; C.D. Vera Donoso; Daniel Vergho; Eric Wallen; Richard Zigeuner

doi:10.1002/jso.24395

August 26, 2016Journal of Surgical OncologyOpen Access

Renal cell carcinoma with inferior vena cava involvement: Prognostic effect of tumor thrombus consistency on cancer specific survival

View Full Paper

Ask AI

Bookmark

Share

Why the study?

Does tumor thrombus consistency affect cancer specific survival in patients with renal cell carcinoma and inferior vena cava involvement?

Key Points

Assess whether tumor thrombus consistency independently predicts cancer-specific survival in patients with renal cell carcinoma extending into the inferior vena cava.
Evaluated cancer-specific survival outcomes in a large cohort of patients presenting with renal cell carcinoma and inferior vena cava tumor extension.
Investigated tumor thrombus consistency as a prognostic factor for inclusion in clinical risk stratification models.
Tumor thrombus consistency demonstrates no independent association with cancer-specific survival in patients with renal cell carcinoma (effect sizes, hazard ratios, and p-values not reported in abstract).
Omitting tumor thrombus consistency from risk stratification algorithms is recommended due to its lack of independent prognostic significance.

Structured PICO

Does tumor thrombus consistency affect cancer specific survival in patients with renal cell carcinoma and inferior vena cava involvement?

P

Population

Patients with renal cell carcinoma (RCC) and inferior vena cava involvement

I

Intervention

Tumor thrombus consistency (TC)

O

Outcome

Cancer specific survivalhard clinical

Tumor thrombus consistency is not independently associated with survival in RCC patients with IVC involvement and should not be used for risk stratification.

Ask about this paper

Answers are grounded in this paper and cite their sources.

Implication

Does not support using tumor thrombus consistency for prognostication in RCC with IVC involvement; leaves open its value in prospective validation.

Abstract

No abstract yet. The journal hasn't published one we can show.

Discussion

No takes yet. Share an insight, caveat, or question.

Cite This Study

Mager et al. (2016) studied this question.

synapsesocial.com/papers/69d721f2236f4746d4563a19 https://doi.org/10.1002/jso.24395

View Full Paper

Ask AI

Bookmark

Share

Renal cell carcinoma with inferior vena cava involvement: Prognostic effect of tumor thrombus consistency on cancer specific survival

Key Points

Structured PICO

Ask about this paper

Implication

Abstract

Discussion

Cite This Study

Renal cell carcinoma with inferior vena cava involvement: Prognostic effect of tumor thrombus consistency on cancer specific survival

Key Points

Structured PICO

Ask about this paper

Implication

Abstract

Discussion

Cite This Study

Keep reading

Keep reading