Key result
Venous thrombus in localized renal cell carcinoma is linked to increased recurrence and worse survival.
Why the study?
Does the level of venous thrombus involvement affect prognosis in patients with renal cell carcinoma?
Cohort (n=880)
Does the level of venous thrombus involvement affect prognosis in patients with renal cell carcinoma?
p-value: p=0.005
In localized renal cell carcinoma, inferior vena cava involvement above the diaphragm confers a worse prognosis than involvement below the diaphragm or in the renal vein, supporting the 1997 TNM classification.
No takes yet. Share an insight, caveat, or question.
May refine prognostic counseling by thrombus level in localized RCC; leaves open whether management should differ by IVC extent.
Kim et al. (2004) conducted a cohort in Renal cell carcinoma (n=880). Venous involvement (renal vein or inferior vena cava) vs. No venous involvement was evaluated on Risk of recurrence (p=0.005). In patients with localized renal cell carcinoma, venous thrombus increased the risk of recurrence (p=0.005), while inferior vena cava involvement above the diaphragm worsened survival (p=0.020).
Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context: