Complement-Binding Anti-HLA Antibodies and Kidney-Allograft Survival

Key Points

• The study aims to evaluate the use of complement-binding capacity of donor-specific anti-HLA antibodies for risk assessment of kidney-allograft loss.
• Assessed the complement-binding capacity of donor-specific anti-HLA antibodies in patients.
• Identified high-risk patients based on antibody profiles.
• Patients identified with high complement-binding antibodies showed increased risk for kidney-allograft loss.