September 11, 2025Open Access

Beta-blockers in Patients with Heart Failure with Reduced Ejection Fraction and Concomitant Chronic Obstructive Pulmonary Disease: Cardiovascular and Respiratory Outcomes

BBBenedikt N. BeerHeart Failure & Transplant LBLina BensonHeart Failure & Transplant CBChristian BasileHeart Failure & Transplant

Structured PICO

Does beta-blocker use reduce cardiovascular death or total heart failure hospitalization in patients with HFrEF and concomitant COPD?

Population

Patients with Heart Failure with Reduced Ejection Fraction (HFrEF) and concomitant Chronic Obstructive Pulmonary Disease (COPD)

Intervention

Beta-blockers

Outcome

Cardiovascular death or total heart failure hospitalization (HHF)composite

Beta-blockers are associated with improved cardiovascular outcomes in patients with HFrEF and COPD without increasing the risk of respiratory exacerbations.

Abstract

In patients with HFrEF and COPD, beta-blocker use was associated with lower risk of cardiovascular death/total HHF, without evidence of safety concerns for COPD exacerbations.

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Cite This Study

Beer et al. (Thu,) studied this question.

synapsesocial.com/papers/69d72894a98988943d563a82 https://doi.org/https://doi.org/10.1002/ejhf.70046

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