Gli proteins encode context-dependent positive and negative functions: implications for development and disease

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Synapse has enriched 3 closely related papers on similar clinical questions. Consider them for comparative context:

1. 1Identification of an Amplified, Highly Expressed Gene in a Human Glioma1987 · 686 citations
2. 2<i>Gli2</i> is required for induction of floor plate and adjacent cells, but not most ventral neurons in the mouse central nervous system1998 · 495 citations
3. 3Expression of <i>wingless</i> in the <i>Drosophila</i> embryo: a conserved <i>cis</i>-acting element lacking conserved Ci-binding sites is required for <i>patched</i>-mediated repression1998 · 51 citations