Why the study?
Does serial high sensitivity cardiac troponin T (hs-cTnT) measurement predict 180-day cardiovascular mortality in patients with acute heart failure?
Does serial high sensitivity cardiac troponin T (hs-cTnT) measurement predict 180-day cardiovascular mortality in patients with acute heart failure?
Serial measurements of hs-cTnT provide prognostic value for 180-day cardiovascular mortality in patients with acute heart failure.
Serial hs-cTnT may refine 180-day CV mortality risk stratification in AHF; hypothesis-generating and should not yet change practice.
Hs-cTnT was elevated above the 99% URL in the majority of AHF patients. Baseline, peak, and peak change hs-cTnT were associated with worse outcomes, with the strongest relationship with 180-day cardiovascular mortality.
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Felker et al. (2015) studied this question.
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