⌘+K

Pulse Explore Communities Researchers Journals

Home Communities Explore

February 25, 2019Clinical Infectious DiseasesOpen Access

Association Between Antibiotic Use and Hospital-onset Clostridioides difficile Infection in US Acute Care Hospitals, 2006–2012: An Ecologic Analysis

Sophia V. Kazakova James Baggs L. Clifford McDonald Sarah H. Yi Kelly M Hatfield Alice Guh Sujan Reddy John A. Jernigan

View Full Paper

Ask AI

Bookmark

Share

Ask about this paper

Answers are grounded in this paper and cite their sources.

Ask your own question…

Abstract

At an ecologic level, reductions in total AU, use of fluoroquinolones, and use of third- and fourth-generation cephalosporins were each associated with decreased HO-CDI rates.

Discussion

No takes yet. Share an insight, caveat, or question.

Cite This Study

Kazakova et al. (2019) studied this question.

synapsesocial.com/papers/69d72ffcb54ccf0cfef306d4 https://doi.org/10.1093/cid/ciz169

View Full Paper

Ask AI

Bookmark

Share

Keep reading

Synapse has enriched 10 related papers. Consider them for comparative context:

1Burden of <i>Clostridium difficile</i> Infection in the United StatesOriginal Research · 2015 · 2,642 citations
2Multistate Point-Prevalence Survey of Health Care–Associated InfectionsOriginal Research · 2014 · 3,928 citations
3Receipt of Antibiotics in Hospitalized Patients and Risk for <i>Clostridium difficile</i> Infection in Subsequent Patients Who Occupy the Same BedRetrospective Study · 2016 · 133 citations
4An evaluation of the impact of antibiotic stewardship on reducing the use of high-risk antibiotics and its effect on the incidence of Clostridium difficile infection in hospital settingsRetrospective Study · 2012 · 163 citations
5Impact of a Reduction in the Use of High-Risk Antibiotics on the Course of an Epidemic of Clostridium difficile-Associated Disease Caused by the Hypervirulent NAP1/027 StrainRetrospective Study · 2007 · 328 citations
6Effects of control interventions on Clostridium difficile infection in England: an observational studyGWAS · 2017 · 322 citations
7Association between <i><scp>C</scp>lostridium difficile</i> infection and antimicrobial usage in a large group of <scp>E</scp>nglish hospitalsRetrospective Study · 2013 · 14 citations
8Estimating National Trends in Inpatient Antibiotic Use Among US Hospitals From 2006 to 2012Retrospective Study · 2016 · 268 citations
9Outpatient Antibiotic Fills and 30-Day Readmission Following Patient-Directed Discharge in Drug Use-Associated Infective Endocarditis in a National Medicaid CohortClinical Infectious Diseases · 2026
10Randomized Trial Comparing Minocycline-EDTA-Ethanol Lock to Standard-of-Care Antibiotic Lock for Management of Central Line–Associated Bloodstream InfectionClinical Infectious Diseases · 2026

More from Clinical Infectious Diseases

More from Centers for Disease Control and Prevention

More from National Center for Emerging and Zoonotic Infectious Diseases