Why the study?
How do hypocapnea and mild hypercapnea affect heart and brain circulation in normal elderly men?
How do hypocapnea and mild hypercapnea affect heart and brain circulation in normal elderly men?
In healthy elderly men, hypocapnea causes vasoconstriction in both heart and brain, whereas mild hypercapnea increases cerebral blood flow without additional coronary vasodilation.
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May guide CO2 reactivity interpretation in healthy elderly; leaves open effects in cardiovascular disease.
In normal elderly men, hypocapnea produces similar vasoconstriction both in the heart and brain. Mild hypercapnea increased cerebral blood flow but did not have an additional effect to dilate coronary arteries beyond the expected range in response to an increase in cardiac workload.
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Yokoyama et al. (2008) studied this question.
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