Meta-analysis reveals narrowing survival gaps and improving life expectancy in systemic sclerosis, indicating enhanced management despite organ-related mortality risks.
Meta-analysis of observational studies indicates a trend for improvement over the last decades in which the life expectancy of SSc patients approaches that of the general population. A decreasing tendency in the survival differences between the limited and diffuse SSc subgroups was also verified. Internal organ involvements have similarly unfavourable predictive impact on survival.
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Komócsi et al. (2012) studied this question.
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