Why the study?
Does the Kv3.1 potassium channel contribute to high-frequency firing in mouse auditory neurones?
Population
Mouse auditory neurones and CHO cell line expressing Kv3.1
Comparison
Tetraethylammonium blockade and computer… vs Baseline/unblocked state
Design
Preclinical
Authors
Loading...
Animal data implicate Kv3.1 in murine auditory high-frequency firing; leaves open human relevance or therapeutic targeting.
Does the Kv3.1 potassium channel contribute to high-frequency firing in mouse auditory neurones?
The Kv3.1 potassium channel is essential for mouse auditory neurones in the medial nucleus of the trapezoid body to sustain high-frequency firing.
Wang et al. (1998) studied this question.
Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context: