Why the study?
Does serial measurement of hsTnI or cTnI at admission and 3 hours facilitate early diagnosis of AMI in patients with suspected acute coronary syndrome?
Does serial measurement of hsTnI or cTnI at admission and 3 hours facilitate early diagnosis of AMI in patients with suspected acute coronary syndrome?
Serial measurement of hsTnI or cTnI at admission and 3 hours later can facilitate the early diagnosis and rule-out of acute myocardial infarction in patients with suspected ACS.
Answers are grounded in this paper and cite their sources.
May support accelerated AMI rule-out in suspected ACS; leaves open assay-specific validation in broader populations.
Among patients with suspected acute coronary syndrome, hsTnI or cTnI determination 3 hours after admission may facilitate early rule-out of AMI. A serial change in hsTnI or cTnI levels from admission (using the 99th percentile diagnostic cutoff value) to 3 hours after admission may facilitate an early diagnosis of AMI.
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Keller et al. (2011) studied this question.
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