January 8, 2025Cardiovascular Diabetology17 citationsOpen Access

Impact of remnant cholesterol on short-term and long-term prognosis in patients with prediabetes or diabetes undergoing coronary artery bypass grafting: a large-scale cohort study

ZLZhongchen LiLiaocheng People's Hospital CYChunyu YuChinese Academy of Medical Sciences & Peking Union Medical College HZHeng ZhangChinese Academy of Medical Sciences & Peking Union Medical College

Structured PICO

Are remnant cholesterol levels associated with AKI and MACCEs in patients with prediabetes or diabetes undergoing CABG?

Population

Patients with prediabetes or diabetes undergoing coronary artery bypass grafting (CABG)

Intervention

Remnant cholesterol (Remnant-C) levels

Outcome

Acute kidney injury (AKI) and major adverse cardiovascular and cerebrovascular events (MACCEs)composite

Elevated remnant cholesterol is an independent risk factor for adverse outcomes (AKI and MACCEs) in diabetic and prediabetic patients undergoing CABG, particularly those treated with insulin.

Abstract

Remnant-C is associated with AKI and MACCEs in patients with diabetes or prediabetes undergoing CABG. The MACCE risk associated with remnant-C is independent of LDL-C and is more pronounced in insulin-treated patients.

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