Why the study?
Opioid therapy for postsurgical pain causes undesired side effects, prompting the need to evaluate nonopioid multimodal therapies to improve pain control and reduce opioid use in colorectal surgery ERAS protocols.
Multimodal pain management in ERAS protocols for colorectal surgery improves pain control, reduces opioid use, and facilitates recovery.
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Supports multimodal analgesia in ERAS for colorectal surgery; leaves open confirmation via randomized trials.
Pain control is an integral part of Enhanced Recovery after Surgery (ERAS) protocols for colorectal surgery. While opioid therapy remains the mainstay of therapy for postsurgical pain, opioids have undesired side effects including delayed recovery of bowel function, respiratory depression, and postoperative nausea and vomiting. A variety of nonopioid systemic medical therapies as well as regional and neuraxial techniques have been described as improving pain control while reducing opioid use. Multimodal and preemptive analgesia as part of an ERAS protocol facilitates early mobility and early return of bowel function and decreases postoperative morbidity. In this review, we examine several multimodal therapies and their impact on postoperative analgesia, opioid use, and recovery for patients undergoing colorectal surgery.
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Simpson et al. (2019) studied this question.
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