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What are the age- and sex-specific reference intervals for IGFBP-3 and the IGF-I to IGFBP-3 ratio measured by new automated chemiluminescence assays across the life span?
What are the age- and sex-specific reference intervals for IGFBP-3 and the IGF-I to IGFBP-3 ratio measured by new automated chemiluminescence assays across the life span?
Provides new age- and sex-specific reference intervals for IGFBP-3 and the IGF-I/IGFBP-3 ratio using automated chemiluminescence assays, highlighting distinct sex differences across the lifespan.
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Establishes assay-specific IGFBP-3 and IGF-I/IGFBP-3 references; supports refined interpretation but leaves open prospective validation.
We present an extensive set of assay-specific age- and sex-adjusted normative data for concentrations of IGFBP-3 and the molar IGF-I to IGFBP-3 ratio and demonstrate distinct sex specific differences across the life span.
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Friedrich et al. (2014) studied this question.
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