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October 1, 2002Journal of Endocrinology

IGFBPs function as pleiotropic molecules, acting both as traditional carrier proteins to prolong IGF half-life and as independent growth factors regulating processes like bone formation.

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SMSubburaman MohanDBD J Baylink

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Overview

IGFBP pleiotropy may guide bone metabolism studies; leaves open clinical translation pending prospective validation.

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Mohan et al. (2002) studied this question.

synapsesocial.com/papers/6a92eb815061e05975bb656ahttps://doi.org/10.1677/joe.0.1750019
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