Answers are grounded in this paper and cite their sources.
Our data revealed that in patients with T2D, high-glucose-enhanced FTO mRNA expression resulted in a decrease in m6A. The lower m6A content might be responsible for the upregulation of methyltransferases. Additionally, FTO induced mRNA expression of FOXO1, G6PC, and DGAT2 and was closely associated with glucose metabolism.
No takes yet. Share an insight, caveat, or question.
Yang et al. (2018) studied this question.
Synapse has enriched 10 related papers. Consider them for comparative context: